Health
One of the keys to long-term success is to avoid mistakes, unforced errors.
This summary traces the efforts of David Sinclair of Harvard, to slow or reverse aging and other age-related realities. He says, "Aging can be slowed or reversed, and we are about to figure out how."
According to a Wall Street Journal article, he has founded the following companies. None of them have gained traction.
- Animal Biosciences. Reversed aging in dogs.
- Calico Life Sciences. Launched by Google.
- New Limit. A cell re-programming company.
- Altos Labs. Cell rejuvenation.
- Sirtris Pharmaceuticals. Red wine and resveratrol.
- OvaScience. Helping "older" women become pregnant.
- CohBar. Treatments for obesity and fatty liver disease.
- Life Biosciences. Genetic reprogramming for vision loss.
- Metro International Biotech. Seeking to develop a formulation to treat age-related conditions such as Alzheimer’s disease. Being marketed to consumers as a longevity-promoting supplement.
- Fully Aligned. A consumer wellness company featuring Serena Poon, celebrity chef.
- Tally Health. Developing a cheek-swab test to tell people their biological age.
Sinclair admits that “Developing medicines that safely and effectively target aging is a difficult endeavor that has turned out to take longer than I expected.”
The Food and Drug Administration, where approval for longevity drugs is administered, doesn’t consider aging a disease.
The holy grail of longer lives continues to be elusive. Don't make an unforced error in its pursuit.
Wealth
Here are two wildly diverse strategies for investing at the edges.
At the hard money edge is owning a core of U.S. Treasury securities. They pay reasonable rates and are fully guaranteed by the full faith and credit of the United States government.
At the easy money edge is to own some kind of cryptocurrency like Bitcoin. Despite friendlier tones being expressed by the incoming administration, our view remains that cryptocurrencies don't meet the standards of an investment. No earnings, no cash flow, no dividends, no interest, no use case.They are a pure speculation.
At the end of the day, the lure of "Easy Money" requires parting with your hard earned
cash to earn even more. "Hard Money" takes years to
build and doesn't depend on a gimmick, popularity, or single investment.
We're sticking with Hard Money. You're welcome.
💥IMPORTANT! This is not specific investment advice! If either of these possibilities appeal to you, please contact us before you do anything. There are important details that must be covered.
Wisdom
In Nature, this is the season of darkness, rest, silence. Silent Night, Holy Night. Visions of sugar plums. This poem seems to strike the right notes.
Let the eyes sparkle with joy,
The mind be filled with possibility,
The heart strong with courage
And your only boundary is joy.
Go. Believe.
You can do anything. It is all possible.
Allow yourself to breath-in the openness of possibility.
Release all barriers of the mind.
Let the soul rise with love and passion.
Allow yourself to dream.
You're too precious to not.
Erica Valentine, Just Breathe
Blessings for this Holiday Season and Best Wishes for a Fulfilling New Year.
Jim Cosgrove, Partner, San Jose, CA jimcos42@gmail.com 408-674-6315
Evidence-based. Rules-driven. Policy-focused. 
